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Peri–implantitis is probably one of the main causes of implant loss.

This article discusses the introduction, etiopathogenesis, diagnosis of peri-implant diseases, and the maintenance, care and treatment of peri-implant infection in osseointegrated implants.

Lesions are called ‘inactive’ when the radiological findings are not comparable with the clinical findings and/or the patient’s symptoms.

A clinically asymptomatic, periapical radiolucency (which is usually caused by placement of implants that are shorter than the prepared osteotomy)is to be considered as inactive .

However, dental implants can lose supportive bone,even in cases of successful osseointegration.Keywords: Peri-implantitis, Implant-failure, Resonance frequency analysis, Regeneration The use of dental implants for supporting prosthetic rehabilitations has shown highly satisfactory results regarding restoration of the patient’s function and esthetics, as well as in terms of long-term survival.However, dental implants can loose supportive bone, even in cases of successful osseointegration.The epithelium and the interface between the supra-alveolar connective tissue and the titanium surface of an implant differ from the interface of the dental-gingival unit.The outer surface of the peri-implant mucosa is lined by a stratified keratinized oral epithelium that is continous with a junctional epithelium attached to the titanium surface by a basal lamina and by hemidesmosomes.The causes of late failure may be marginal infection/disease or biomechanical overload.

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